NEW SYNTHESIS OF LUMATEPERONE TOSYLATE

Cet ouvrage présente les travaux du groupe d'experts réunis par l'INSERM dans le cadre de la procédure d'expertise collective, pour répondre aux questions ...







[pastel-00000949, v1] Vers la synthèse totale de la paulitine - UCP
This study was done in a time-resolved fashion, collecting products at reaction times of 1, 2, 3, 6, and 9 h. Gaseous products of MeOH reforming ...
Analysis of gas chromatography/mass spectrometry data for catalytic ...
The methyl ester was consumed, however, formation of a large amount of the 2,5-diacid was observed. The reaction was quenched with 2 N HCl and extracted with ...
Synthetic strategies for the application of anodic coupling to the ...
A precipitate formed was filtered, washed with MTBE, and dried under reduced pressure. 1-(2,2-Dimethoxyethyl)cyclobutane-1-carbonitrile (2a). Yield: 91 g, 82% ( ...
An Efficient and Highly Diastereoselective Synthesis of ... - AWS
We here report the preparation of a new 2,6,8-trisubstituted bicyclic tripeptidomimetic scaffold through TFA- mediated cyclization of a linear ...
Synthesis of a novel tripeptidomimetic scaffold and biological ...
General method for the preparation of ?-carbolines (compounds 2, 3, 4, 8, 10). To a solution of tryptophan or tryptophan methyl ester or 2-amino-3-(1H-indol-3- ...
University of Groningen Industrial applications of multiple bond ...
(2,2-dimethoxyethyl)-3-methoxy-O-methyltyrosinamide 15e. This residue was purified by flash chromatography (7:3 hexane/EtOAc) to give 15e (82%) as a white solid.
Synthesis of ?-carboline derivatives - Sciforum
A single intraperitoneal injection (0.6 ml/kg) of dimethoxyethyl phthalate (DMEP) was given to groups of Wistar strain rats on day 10, 11, 12, ...
Experimental Methods - The Royal Society of Chemistry
l'ester boronique 18a synthétisé dans le chapitre 2. Elles ont permis d ... 2-(2,2-Diméthoxyéthyl)-3-((4,4,5,5-tétraméthyl-1,3,2-dioxaborolan-2-yl ...
Thèse de Tiphaine Dedours, Université de Lille, 2020
... ester de carbonate. Cette étape est suivie par l'attaque d'un ... 2-(2,2-diméthoxyéthyl) phényl isonitrile comme isonitrile convertible dans ...
THESE DE DOCTORAT
... 2,2-Dimethoxyethyl)-N,?-dimethylbenzenemethanamine (5m). The title compound was prepared according to GP1 using boronic ester 1 (0.118 g,. 0.508 mmol) and 2,2 ...
Cu-Catalysed Coupling of Aliphatic Amines with Alkylboronic Esters
... 2,2-Dimethoxyethyl)-N,?-dimethylbenzenemethanamine (5m). The title compound was prepared according to GP1 using boronic ester 1 (0.118 g,. 0.508 mmol) and 2,2 ...
Cu-catalyzed coupling of aliphatic amines with alkylboronic esters
The reaction mixture was sampled at the end of the required reaction time and the conversion was determined by HPLC with reference to a 0.05M caffeine solution.