Hypersensitivity to nonsteroidal anti-inflammatory drugs
Treatment of AERD consists of avoidance of aspirin or non-selective COX inhibitor NSAIDs. AERD patients can safely use selective COX-2 inhibitor NSAIDs or ...
Long-term tolerability of etoricoxib in different types of NSAID ...NSAIDs are to be prohibited in patients with. Fernand Widal syndrome or who have a history of atopy or asthma. has demonstrated an increase in the incidence of ... Guidelines for the management of asthma in adults - TACDiverted arachidronate to this pathway after inhibition of COX by NSAIDs causes increased formation of leukotrienes, which are also mediators of inflammation.1. COX-2 ???? ????? ?? ???? ?????? 1????? ???? ????? ??? ?? ????. ? NSAIDs? ??????? ??? ?? ???? ?. ?? COX-2 ???? celecoxib?? ????? ??. ?? ... ??? ???? - ???????????-?? ??(??? ???(eosinophilic phenotype) ?? ?. ? ?? ????????? ??? ??? ?? ?? ?? ??). ????? ??? ?? ?? ? ... ?? ??????? ???? ?? ?? ????? ?? ??, ??, ??? ??/??. ?? ???. ?? ??? ???? ??, ??, ???? ?? ??. ? ???? ... ??????? ???(NSAIDs) ??? ?? ??? ??? ???? ibuprofen ???? ??? ???. ??? ???? ?? ?????. ????, ??, ??. ???? ?? ??? ?? ???? ?????? ?. ??????????????????????? ?????????????????????????GB/T 51366 ???? 2.????????????????????GB/T 51366 ???????????? ... ?????????????1 ???????????????????????????????????. ????????????HRB400 ??????????????????????. ??HPB300 ... ??????????10G409??. ?????????????????????????????????. ????????????????????????????????? ... ??????????????2019 ???? ???EU-01-01 ???????; ?. EU-01-02 ?????????. ??????????????????????????????????. ?????????????? ... ??????????????????????????????????????. ??????????????????????????fb=3.6HB?????. ????????????????GB/T1172?1999 ... ???????????????????????????. ?????????????????????????????????. ????????????????????????????????.
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