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10F - ????1. ????2025/4/1(?)~5/31(?),??????????????? 2.75?(?) ... ??10F OSIM/??/??/OGAWA?????????. 5000?????500???? ... ????????????????2030 ?????????????????4 ... ?? ? 2025 ? 1 ? 1 ? ? ?? ? ?? ? ?? ? ??? ? ? ?. ? ? ? ? ? ? ... ?? - ?????????????????????????????. (Frequency-domain analysis, FD) ??????(Time- domain analysis, TD)???????????????. ??? ... ??????????:(1)???-skm points 100?,??6/5(?)-6/30(?)???????????????????????-skm points 300?,??6/5(?)-6/30(?) ... ??2025?1???????CES ???2025??AI??????????. AI???????????????????????????????. ??AR/VR/XR ??????AI ... Identification of a Molecularly-Defined Subset of Breast and Ovarian ...These studies support the use of PARPi-ATRi for the treatment of ovarian cancers that progress on PARPi in the clinic. Results. Genomic instability and ... Role of Biomarkers in the Development of PARP InhibitorsLe traitement de maintenance par PARPi après réponse au platine en rechute sensible a été étudié dans 4 essais randomisés contrô- lés vs placebo, réalisés dans ... Expanding the Perspective on PARP1 and Its Inhibitors in Cancer ...We assessed the effects of the PARPi. Olaparib on cell viability, homologous recombination, and DNA repair. We assessed underlying. Epigenetic and Genomic Hallmarks of PARP-Inhibitor Resistance in ...Abstract. Poly(ADP-ribose) polymerases (PARP) are enzymes involved in DNA-damage repair. Inhibition of PARPs is a promising strategy for targeting cancers ... PARP1 Inhibition Radiosensitizes Models of Inflammatory Breast ...We report here analysis of outcome of PARPi treatment in patients including those with platinum resistant disease. Methods: In this study, we analyzed efficacy ... Combining PARP with ATR inhibition overcomes PARP inhibitor and ...PARPi are an area of active clinical investigation in oncology as they (1) exploit synthetic lethality in tumours with defective homologous recombination (HR) ... Prise en charge médicale de la récidive du cancer épithélial de l ...Abstract: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) induce cytotoxic effects as single agents in tumors characterized by defective ...
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