The DNA damage response - from cell biology to human disease
Abstract: DNA lesions arise from a combination of physiological/metabolic sources and exogenous environmental influences.
DNA damage in cancer development: special implications in viral ...Similar to exogenous DNA damage, inherent DNA repair defects in tumours may also increase the production of cytosolic DNA and appear to ... Transcriptional responses to DNA damage - IDEKER LABExogenous DNA damage, on the other hand, occurs when environmental, physical and chemical agents damage the DNA. Examples include UV and ionizing radiation, ... Replication Stress, DNA Damage, Inflammatory Cytokines ... - HALFormation of cytoplasmic inclusions (CIs) of TDP-43 and FUS, along with DNA damage accumulation, is a hallmark of affected motor neurons in ...
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