The DNA Damage Repair Response - Clinics of Oncology
DDR attenuation induces EMT in epithelial normal and neoplastic cells, that can be further stimulated by exogenous DNA damage. ... Halazonetis, ...
The DNA damage response - from cell biology to human diseaseAbstract: DNA lesions arise from a combination of physiological/metabolic sources and exogenous environmental influences. DNA damage in cancer development: special implications in viral ...Similar to exogenous DNA damage, inherent DNA repair defects in tumours may also increase the production of cytosolic DNA and appear to ... Transcriptional responses to DNA damage - IDEKER LABExogenous DNA damage, on the other hand, occurs when environmental, physical and chemical agents damage the DNA. Examples include UV and ionizing radiation, ...
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