PARP1 Inhibition Radiosensitizes Models of Inflammatory Breast ...
We report here analysis of outcome of PARPi treatment in patients including those with platinum resistant disease. Methods: In this study, we analyzed efficacy ...
Combining PARP with ATR inhibition overcomes PARP inhibitor and ...PARPi are an area of active clinical investigation in oncology as they (1) exploit synthetic lethality in tumours with defective homologous recombination (HR) ... Prise en charge médicale de la récidive du cancer épithélial de l ...Abstract: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) induce cytotoxic effects as single agents in tumors characterized by defective ... SETD1A-dependent EME1 transcription drives PARPi sensitivity in ...PARPi have been largely adopted in triple-negative metastatic breast cancer, but their place has been less clearly defined in endocrine-receptor ...
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