SETD1A-dependent EME1 transcription drives PARPi sensitivity in ...
PARPi have been largely adopted in triple-negative metastatic breast cancer, but their place has been less clearly defined in endocrine-receptor ...
The role of PARP in DNA repair and its therapeutic exploitationPARPi. In malignant cells with integral DDR mechanisms,. PARPi could be used in combination with DNA-damaging agents to increase radiosensitivity ... Role of PARP Inhibitors in Cancer Immunotherapy: Potential Friends ...PARPi treatment which directly cleaves GSDME and, subsequently induces pyroptosis. PARP Inhibitors: A Major Therapeutic Option in Endocrine-Receptor ...Poly(ADP-ribose) polymerase. (PARP) inhibitor (PARPi) is a DNA repair enzyme associated with DNA damage repair. PARPi takes PARP as a target to ... (12)??????(A) - Googleapis.com????????????????????????????. ???????????????1?2????????????. ??????????? ... Bunseki 2023 - ????TC-01A?????????. ????????????. ?????????????. ????????????. ???????? ????????? ... ???????????????????????? ... - NEDO??????. ???????????????????????? LDH ????? ... ??????????????????????????????????????. ?????????????? ??????????????? ...??????????????????????????????????????? ?????????LFPI???????????????????????????. GCMS-TQ8050 NX - ?????????????????????????????. ????????????????????????. ????????????????????????. ????? ... ??????????????????????????????????????. ??????????????????????????? ... ??? ? ??????? ??????????????????????. ??????? ... ???? ????????? ??? ???? Suzuki Mikio????????????????????????? ?????????????? ... ???? (????) ??????? (????) ????. ???? ... ??????????????????? ?????... ?????????. ???????????????[1-109]? ????????????????????????????????????????. ??????? ... 1????????????? 2???????????? 3?? ...??????????????????????????????????????? ???????????????????????????????????????????????.
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