TREM2 macrophages drive NK cell paucity and dysfunction in lung ...
Context: Glioblastoma is the most aggressive brain tumor, with a median survival not exceed- ing 15 months after diagnosis.
Evolution of the Tumor Microenvironment toward ... - eScholarshipIn triple-negative breast cancer (TNBC), the benefit of combining chemotherapy with checkpoint inhibitors is still not very clear. We utilize ... High-density gene expression analysis of tumor-associated ...Trem2 deletion caused reduced tumor progression in sarcoma and triple-negative breast cancer xenografts (Fig. S2A). Gross histological ... Triggering receptor expressed on myeloid cells 2 (TREM2 ... - bioRxivThese observations suggested different predisposition for the two growth patterns by human breast cancer cells in initiating brain colonization.
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