Mapping eQTLs With RNA-Seq Reveals Novel SLE Susceptibility ...
Applied to type 2 diabetes (T2D) and systemic lupus erythematosus (SLE), scPrediXcan outperformed the canonical TWAS framework by identi- fying ...
Multiancestral Genomic Approach to SLE Precision Medicine - DTICSystemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. Th`ese de Doctorat PLA2R1 et THSD7A, deux auto-antig`enes de la ...Human leukocyte antigen region. SNP analyses within the HLA region provided strong evidence of association with SLE across groups (Fig. 2). Dissecting the Genetic Basis of Systemic Lupus ErythematosusGlucocorticoids (GCs) exert powerful anti-inflammatory effects and therefore have been a mainstay in the treatment of. SLE, especially in moderate and severe ...
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