Deconvolution and Phylogeny Inference of Diverse Variant ... - bioRxiv
Abstract. Motivation: Reconstructing clonal lineage trees (?tumor phylogenetics?) has become a core tool of cancer genomics.
joint inference of single- nucleotide variants and cell phylogeny from ...Both. SIEVE and CellPhy agreed that TP and TD cells were closer than TC cells during the evolutionary history. The fact that the different ... Probabilistic graphical models for inferring tumor phylogeny and ...They performed the CRC28 scDNA-seq experiment, pre-processed the scDNA- seq datasets, provided insightful input and feedback to the models and the analyses ... Genome-wide link between DNA replication and genome instability ...Coloured cells indicate an association between the SV type and muted gene. TD: Tandem Duplications; small: <50-kb; mid: 50-500kb; large: >500kb.
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