Clinical-Pharmacokinetics-of-Allopurinol.pdf - ResearchGate
A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout. Curr Rheumatol Rep 2009;11:135?40. 166 Stocker ...
CLINICAL PRACTICE GUIDELINES FOR MANAGEMENT OF GOUTThe serum uric acid concentration, which reflects this pool, should be maintained below 6.5 mg/dL. Do not start allopurinol during an acute attack of gout. Asymptomatic hyperuricemia: To treat or not to treatA lower SUA target (<5 mg/dL; 300 mmol/L) to facilitate faster dissolution of crystals is recommended for patients with severe gout (tophi, ... CLINICAL GUIDELINE - Management of Acute and Recurrent GoutFebuxostat (40 mg/d) and allopurinol (300 mg/d) are equally effective at decreasing serum urate levels, and prophylactic therapy with low-dose colchicine or low ...
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