Characterizing Stress Granule Assembly and ... - UC Davis
Inhibition of G3BP1 by expression of its acidic or 'B-domain' accelerates axon regeneration after nerve injury bringing a potential therapeutic ...
University of Groningen Human G3BP1 interacts with beta-F1 ...G3BP1 condensation in cells reduces global translation. Stress-induced G3BP1 condensation is linked to global transla- tion arrest. To test if ... Optogenetic control of the integrated stress response reveals ...This work highlights G3BP1 granule disassembly as a potential therapeutic strategy for enhancing axon growth and neural repair. CNS injury | ... Recruitment of endoplasmic reticulum-targeted and cytosolic ... - NETThe molecular basis for stress granule assembly is a network of protein-RNA interactions with G3BP1 as the central node and molecular switch ...
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